Hero Lab Online is a web-based product that provides access through the browser on nearly all modern devices. As a server-based product, there is a nominal, ongoing service fee. Hero Lab Classic is a desktop product that runs locally on the computer, with iPad support for two games. Demo versions of each are available (Online and Classic).

Hero Lab supports many game systems. These game systems, and the content from various supplements for the game systems, are purchased as add-ons to the core product, unlocking the material permanently.

Hybrid game systems offer support for both the Online and Classic forms. New Hero Lab users receive both access through the Online platform and a Classic license for use on the desktop. Existing Classic users can add Online access or continue using the desktop product. Game systems and content unlocked for Hybrid game systems is available equally on both platforms. However, the two platforms are distinct, and the ability to move characters between them is very limited.